Muscle Physiology

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Muscle Physiology and Modeling

Because they are so important for survival, muscles have evolved many complex features that enhance their strength, speed, efficiency and controllability. The model presented here consists of quantitative functions that represent each of the anatomical structures and physiological processes that underlie such features in typical mammalian skeletal muscles. These include the processes of recruit...

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Skeletal Muscle Physiology

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The structural basis of current contraction theories is the double array of thick and thin myofilaments revealed by the electron microscope. The physiologic properties that characterize the contractile process are natural consequences of this structure if (a) during shortening the 2 sets of filaments move relative to each other and (b) the flux of chemical energy through the contractile mechani...

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Muscle Physiology and Contraction Theories

The structural basis of current contraction theories is the double array of thick and thin myofilaments revealed by the electron microscope. The physiologic properties that characterize the contractile process are natural consequences of this structure if (a) during shortening the 2 sets of filaments move relative to each other and (b) the flux of chemical energy through the contractile mechani...

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in this area, especially the physiological significance of the full range of interactions within and between thick and thin filament proteins. An ultimate challenge is to develop a comprehensive model of conformational changes of thick and thin filament proteins and of intermolecular interactions underlying activation, as well as force generation and shortening, in skeletal muscle with high tem...

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ژورنال

عنوان ژورنال: Nature

سال: 1959

ISSN: 0028-0836,1476-4687

DOI: 10.1038/1831008b0